Far Eastern Mathematical Journal

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Optimal multiplicative control of a semilinear parabolic equation


Chebotarev A.Yu.

2023, issue 2, P. 270-277
DOI: https://doi.org/10.47910/FEMJ202324


Abstract
An analysis of optimal control problems for a nonlinear parabolic initial-boundary value problem that models the dynamics of the collective behavior of a bacterial community is presented. Estimates for the solution of the initial-boundary value problem are obtained, the solvability of control problems is proved, and optimality conditions are derived. The weak "bang-bang" principle is set for the problem with the final observation.

Keywords:
optimal control problems, optimality system, semilinear parabolic equation, multiplicative control.

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References

[1] S. T. Rutherford, B. L. Bassler, “Bacterial quorum sensing: its role in virulence and possibilities for its control”, Cold Spring Harb. Perspect. Med., 2 (2012), a012427.
[2] A. K. Bhardwa, K. Vinothkumar, N. Rajpara, “Bacterial quorum sensing inhibitors: attractive alternatives for control of infectious pathogens showing multiple drug resistance”, Recent Pat. Antiinfect. Drug Discov., 8 (2013), 68–83.
[3] C. Kuttler, A. Maslovskaya, “Hybrid stochastic fractional-based approach to modeling bacterial quorum sensing”, Math. Model., 93 (2021), 360–375.
[4] A. Maslovskaya, C. Kuttler, A. Chebotarev, A. Kovtanyuk, “Optimal multiplicative control of bacterial quorum sensing under external enzyme impact”, Math. Model. Nat. Phenom., 17 (2022), 29.
[5] A. D. Ioffe, V. M. Tikhomirov, Teoriia ekstremal'nykh zadach, Nauka, Moskva, 1974.
[6] A. V. Fursikov, Optimal'noe upravlenie raspredelennymi sistemami. Teoriia i prilozheniia, Nauchnaia kniga, Novosibirsk, 1999.
[7] J-L Lions, E. Magenes, Non-homogeneous boundary value problems and applications, Springer-Verlag, New York, 1972.

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